Every cell holds the complete picture

Now you can see it

Atrandi Biosciences builds high‑throughput single‑cell analysis tools powered by patented Semi‑Permeable Capsule (SPC) technology – enabling multi‑step workflows that isolate tens of thousands of cells while maintaining single‑cell resolution.

Semi-Permeable
Capsules

A different way to think about single-cell

Most single-cell methods isolate cells in sealed compartments. You can add reagents, but you can’t remove them, exchange buffers, or run chemically incompatible steps in sequence. That single limitation is responsible for nearly every tradeoff researchers make in designing single-cell workflows.
Semi-Permeable Capsules (SPCs) work differently.
The result is a platform that runs like a bulk reaction but delivers single-cell resolution.
No cross-contamination. No compromises on reaction chemistry. Just the data.

Retain cells and nucleic acids – freely exchange small molecules (enzymes, buffers, primers)

Isolate tens of thousands to hundreds of thousands of cells simultaneously

Run multi-step workflows, each step under optimal conditions

How SPCs work

What becomes possible with SPCs?

From profiling complex microbiomes to co-sequencing RNA and DNA from the same cell – here’s what opens up when the compartment stops being the constraint.

Single-Cell RNA & DNA
Co-sequencing

Jointly profile RNA and DNA at single-cell resolution – directly connecting genotype and phenotype from the same cell. No inference. No averaging.

Single-Cell
Microbial Genomics

Characterize microbiomes at the level of individual cells. Uncover microbial dark matter, trace horizontal gene transfer, and access what metagenomics misses.

Single-Cell Assay
Innovation

Your workflow – at single-cell resolution. Have a multiomic assay you want to scale? SPCs are designed to be adapted. Bring your biology, and build at throughput that makes the experiment meaningful.

Single-Cell
Cultivation

Isolate viable single cells for downstream growth and recovery – at throughput that makes phenotypic selection practical.

Explore applications

Built by scientists.
For scientists.

Single-cell biology has fundamentally changed what we can know about life. But for all the progress, most workflows still force a choice – between throughput and resolution, between scale and multi-step flexibility. Atrandi was founded in 2016 by scientists with deep roots in microfluidics and single-cell sequencing – with one intention: build the tools that let you have both.
We're here to enable.

Our Story

For labs developing novel SPC applications

Full control over throughput, capsule size, and encapsulation parameters. Real-time high-speed imaging so you see exactly what’s happening, and can optimize accordingly.

For established SPC workflows

Load reagents and press a button. Encapsulate up to 100,000 cells in 30 minutes across up to eight samples simultaneously. No microfluidics experience required.

SPC Kits

All the reagents needed to generate Semi-Permeable Capsules (SPCs) and run multi-step single-cell processing through simple pipetting. Designed to support scalable workflows across a wide range of applications.

See full product portfolio

Used in labs at

Not sure
where to start?

Our scientists will help you find the right fit.

Whether you’re exploring SPCs for the first time or scaling an existing workflow, our team is here to help you find the right path – from platform selection to application development.